Stroke and Its Treatment Through TPA

Stroke and Its Treatment Through TPA

When someone suffers an ischemic stroke—caused by a blood clot blocking blood flow to part of the brain—every minute counts. The sooner treatment begins, the better the chances of minimizing lasting damage. One highly effective treatment is TPA (tissue plasminogen activator), a clot‑busting medication that can significantly change the outcome of a stroke.

What Is TPA and How Does It Work?

TPA, also known as alteplase, activates a natural enzyme called plasmin that dissolves blood clots, helping restore blood flow to affected areas of the brain. When given promptly, TPA can save brain cells and reduce long‑term disability by about 50%.

Critical Time Window

TPA must be administered intravenously within 4.5 hours of stroke symptom onset, with earlier treatment offering better outcomes. In fact, FDA in USA has officially approved the use of TPA (tissue plasminogen activator) for ischemic stroke when it is administered within 3 hours of symptom onset. Clinical guidelines across the globe have since extended that window to 4.5 hours for certain eligible patients based on further evidence.

Eligibility & Safety

Not everyone is a candidate for TPA. Doctors evaluate eligibility based on factors such as the time since symptoms began, bleeding risk, recent surgery, blood pressure, and medical history. Before treatment, patients undergo rapid CT scans to rule out bleeding and high blood pressure is managed for safety.

Risks and Monitoring

Major risks include internal bleeding—particularly symptomatic intracranial hemorrhage—which occurs in a small percentage of patients, as well as angioedema (swelling in the throat or mouth), another rare complication. Patel Hospital’s stroke team carefully monitors patients in a stroke unit or ICU, tracking neurological signs, with CT scans used to identify any complications early on.

Choose Patel Hospital for TPA Treatment— Here’s why?

At Patel Hospital, we provide advanced stroke treatment through TPA with a focus on:

• Timely intervention—delivering TPA quickly and efficiently after emergency arrival
• Clot dissolution—targeting damaged areas to restore blood flow
• Specialized care from a team of neurologists, stroke specialists, and ICU nurses
• Risk assessment, ensuring only eligible patients receive treatment
• Multidisciplinary support, including immediate rehabilitation, lab follow‑ups, and ongoing neurological care

These match national standards and ensure patient safety and treatment efficacy.

Take Action: Know the Signs, Act Fast

If you or someone around you shows any stroke symptoms—using the FAST mnemonic (Face droop, Arm weakness, Speech trouble, Time to call 911)—don’t wait. Get to the hospital immediately. Prompt TPA treatment can make a substantial difference in recovery and long-term outcomes.

You can also contact Patel Hospital to book an appointment 021-111-174-174.